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PSPHL (Putative Phosphoserine Phosphatase-like Protein, L-3-phosphoserine-phosphatase Homolog, PSPHP1, CO9)

PSPHL (Putative Phosphoserine Phosphatase-like Protein, L-3-phosphoserine-phosphatase Homolog, PSPHP1, CO9)

Cat no: P4076-85B

Supplier: United States Biological
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Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time. Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P4076-85B
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Kuo CH, Miyazaki D, Nawata N, Tominaga T, Yamasaki A, Sasaki Y, Inoue Y. Prognosis-determinant candidate genes identified by whole genome scanning in eyes with pterygia. Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3566-75.
Additional info: Recognizes PSPHL. Species sequence homology: Human.

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