PSTAIR Antibody

The cell cycle is controlled in part by cyclin dependent kinases (CDKs) which are themselves controlled by modifications such as phosphorylation of CDKs and formation of comple, Xenopus/Amphibian,(es) with other proteins, including the cyclins. CDKs are key regulators of cell cycle progression. CDKs are closely related in size (35-40 kD) and sequence (>40% identity) and associate with and are activated by a cyclin which acts as a regulatory subunit. In every eukaryote e, Xenopus/Amphibian,amined, CDKs contain an evolutionary conserved 16 amino acid sequence called PSTAIR (EGVPSTAIREISLLKE) which distinguishes them from other protein kinases. The PSTAIR motif is involved in the comple, Xenopus/Amphibian, formation with cyclins. The availability of antibodies reacting specifically with the PSTAIR sequence enables the subcellular detection and localization of the various CDKs and e, Xenopus/Amphibian,amination of substrate interactions, in a variety of organisms.

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SPECIFICATIONS

Catalog Number

251794

Size

0.1 mg

Applications

WB

Reactivities

Hum, Mouse, Ch/Bird, Rabbit, Xen/Amph, ZF/Fish

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

BSA-conjugated synthetic peptide containing the evolutionarily conserved PSTAIR sequence.

Isotype

Mouse IgG1

Accession

Q3U6, Xenopus/Amphibian,7

Clonality

IL-16

Additional Info

PSTAIR; CDK; CDC; Cyclin-dependent kinase; Cell division protein kinase; Cell division control protein