PTK6 (2H12) Antibody

Cat no: 252696

Supplier: ABBIOTEC

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Description
Additional Information

PTK6 (Protein tyrosine kinase 6) is a 451-amino acid protein (~52kDa),Mouse,ay function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. PTK6 has been shown to undergo autophosphorylation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. E, Xenopus/Amphibian,pressed at low level in some breast tumors, but not in normal breast tissue. Also found in melanocytes, but not e, Xenopus/Amphibian,pressed in heart, brain,Porcinelacenta, lung, liver, skeletal muscle, kidney and pancreas. Overe, Xenopus/Amphibian,pression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Catalogue number:	252696
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q13882
Antigen:	Purified recombinant fragment of human PTK6 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Clonality:	2H12B8
Additional info:	Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK; BRK; PTK6