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Purified anti-Artemis
BioLegend

Supplier:

BioLegend

Cat no: 619802

Purified anti-Artemis

Artemis is a widely expressed 78 kD protein involved in non-homologous end joining. This protein has been reported to be involved in DNA double-strand break repair and the processing of hairpin coding ends during VDJ recombination. Artemis has endonuclease and exonuclease activity and has been shown to be mutated in human severe combined immune deficiency disorder (T-B- radiosensitive SCID). Artemis is phosphorylated by DNA-PKcs; phosphorylation regulates intrinsic endonuclease and exonuclease activity. Artemis has been shown to form a complex with DNA-PKcs. The Poly6198 antibody has been shown to be useful for Western blotting of the human Artemis protein.

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SPECIFICATIONS

Catalog Number

619802

Size

200 microl

Applications

IF, WB

Hosts

Rabbit

Reactivities

Hum

Clone

Poly6198

Antigen

Peptide-KLH (KGLRAPTLKRRLE)

Gene Id

430764

Isotype

Rabbit Polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

Artemis protein

Regulatory Status

RUO

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

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