Purified anti-ATIC

Cat no: 635602

Supplier: BioLegend

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Description
Additional Information

ATIC (AICAR transformylase/IMP cyclohydrolase) belongs to the purH family, expressed in the cytoplasm, predicted molecular weight approximately 65 kD. ATIC catalyzes the penultimate and final steps in the de novo purine nucleotide biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP. AICA-ribosiduria is a recently discovered inherited metabolic disease caused by a defect in final steps of purine de novo biosynthesis. Clone F38P7H9 has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat, frog and fruit fly ATIC.

Catalogue number:	635602
Reactivities:	Human, Mouse, Rat
Hosts:	Mouse
Applications:	Western Blot
Size:	100 microg
Clone:	F38P7H9
Gene:	471
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 microg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Ovalbumin-conjugated synthetic Peptide AHTNLRLFHH
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	PURH, IMPCHASE/AICARFT, Bifunctional purine biosynthesis protein PURH