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Purified anti-Aurora B Phospho (Thr232)

Purified anti-Aurora B Phospho (Thr232)

Cat no: 636101

Supplier: BioLegend
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Aurora B belongs to Serine/threonine kinase family, Aurora subfamily. Predicted molecular weight 39 kD. This kinase is highly expressed in thymus and many cancers and is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and is up regulated in cancer cells during M phase. Aurora B localizes to centromeres in early mitosisand then the spindle midzone in anaphase and is required for histoneH3 phosphorylation, chromosome alignment, centrosome maturation, activation of the spindle assembly checkpoint and cytokinesis. The Poly6361 antibody recognizes human phospho-Aurora B (Thr232) and has been shown to be useful for immunoflorence staining.
Catalogue number: 636101
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence
Size: 25 microl
Clone: Poly6361
Gene: 9212
Dilutions: Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated. For IHC, use a 1:50 dilution of antibody for staining. Antigen retrieval for IHC of formalin-fixed paraffin-embedded tissue using 0.01 M sodium citrate buffer is recommended.
Storage buffer: Upon receipt, store frozen at -20C.
Antigen: Modified peptide
Isotype: Rabbit Polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: AIK2, STK12, AIM1, ARK2, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, Serine/threonine protein kinase 12
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