Purified anti-beta-catenin

Cat no: 650902

Supplier: BioLegend

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Description
Additional Information

beta -catenin is a 94 kD nuclear and cytoplasmic protein containing Armadillo repeats. This protein is involved in cell-cell adhesion and the wingless/WNT signaling pathway, and has been implicated as an oncogene. beta-catenin can be modified by glycosylation, phosphorylation, and ubiquitination to target it for degradation. This protein has been shown to interact with E-cadherin, alpha-catenin, axin, APC, GSK-3beta, and Tcf/Lef. Dissociation from axin allows cytoplasmic accumulation. After nuclear translocation, it binds Tcf/Lef.

Catalogue number:	650902
Reactivities:	Human, Mouse
Hosts:	Mouse
Applications:	Immunofluorescence, Western Blot
Size:	100 microg
Clone:	12E4-2
Gene:	12387
Dilutions:	Each lot of this antibody has been quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Partial beta-catenin recombinant protein
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CTNNB1