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Purified anti-C/EBP beta (2 isoforms C/EBP beta, LAP)

Purified anti-C/EBP beta (2 isoforms C/EBP beta, LAP)

Cat no: 626002

Supplier: BioLegend
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C/EBP beta (also known as CCAAT/enhancer-binding protein beta, interleukin 6-dependent DNA-binding protein, and nuclear factor of interleukin 6 [NF-IL6]) is a member of the basic leucine zipper C/EBP transcription factor family. C/EBP has three isoforms that include C/EBPbeta, LAP, and LIP (35 kD, 32 kD, and 20 kD, respectively). This protein is localized in the nucleus and functions as a transcription factor in immune, inflammatory, acute-phase, cytokine, collagen type I gene expression. It is upregulated by growth hormones and has been shown to interact with CEBP-alpha, CEBP-delta, CEBP-gamma, CEBP-epsilon, and CEBP-zeta. The C/EBP beta protein is known to be modified by phosphorylation and ubiquitination. The A16 monoclonal antibody has been shown to be useful for Western blotting of the mouse 35 kD and 32 kD LAP C/EBP beta isoform.
Catalogue number: 626002
Reactivities: Mouse
Hosts: Mouse
Applications: Western Blot
Size: 100 microg
Clone: A16
Gene: 25301
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store at 4C.
Concentration: 0.5 mg/ml
Antigen: Recombinant full length mouse C/EBP beta protein
Isotype: Mouse IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CCAAT/enhancer-binding protein beta, Alpha-1-acid glycoprotein/enhancer binding protein, Interleukin 6-dependent DNA-binding protein (IL-6DBP), Nuclear factor of interleukin 6 (NF-IL6), Liver-enriched transcriptional activator protein (LAP)
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