Purified anti-CAK (cdk7) Phospho (Ser164/Thr170)

Cat no: 632402

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

CAK (also known as CDK-activating kinase, CDK7 and cell division protein kinase 7 is a 40 kD nuclear protein that is a member of the serine/threonine family of protein kinases, CDC2/CDKX subfamily. CAK activates cyclin-associated kinases CDC2/CDK1, CDK2, CDK4, CDK6 by threonine phosphorylation and controls cell cycle progression, DNA repair, and RNA polymerase II transcription. CAK is activated by phosphorylation at Thr170 and is inactivated by phosphorylation at Ser164. CAK has been reported to interact with cyclin H and MAT1 to form the CAK complex, the CAK complex then interacts with core-TFIIH to form the TFIIH basal transcription factor. The Poly6324 antibody is useful for immunofluorescence microscopy of human CAK protein.

Catalogue number:	632402
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunofluorescence
Size:	100 microl
Clone:	Poly6324
Gene:	1022
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Modified peptide
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	CDK-activating kinase, CDK7, Cell division protein kinase 7