Purified anti-Caspase 2L

Cat no: 634001

Supplier: BioLegend

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Description
Additional Information

Caspase 2 (Nedd-2/ICH-1) is a member of the peptidase family C14 that contains a CARD domain. This caspase has been reported to have two isoforms.The larger protein, Caspase-2L(ICH-1L) possesses proapoptotic activities , whereas Caspase-2S (ICH-1S) is able to inhibit apoptosis.When cells are induced to undergo apoptosis, endogenous Caspase 2 is probably activated early in the apoptotic process by cleaves into three fragments of 33 and 14 kD, and then these are further processed into 18 and 12 kD active subunits. The Poly6340 antibody has been shown to be useful for western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat caspase-2L p12 subunit and precursor (also designated Ich-1L).

Catalogue number:	634001
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunoprecipitation, Western Blot
Size:	125 microl
Clone:	Poly6340
Gene:	8795
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting suggested working dilution(s): Use 25microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C. DO NOT FREEZE.
Antigen:	Peptide mapping to the carboxy terminal of human caspase-2L.
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	ICH-1L, CASP2L