Purified anti-Cdc25A Phospho (Ser17)

Cat no: 620702

Supplier: BioLegend

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Description
Additional Information

Cdc25A (also know as M-phase inducer phosphatase 1 and dual specificity phosphatase Cdc25A) is a 65 kD MPI phosphatase containing a rhodanese domain. This nuclear protein functions as a dosage-dependent inducer in mitotic control required for the progression of cell cycle. Cdc25A activates Cdc2 by dephosphorylation, dephosphorylates CDK2 in complex with cyclin E. Cdc25A is timulated by cyclins B, downregulated by Chk1 and Cds1/Chk2 phosphorylation. This phosphatase has been shown to interact with Cdc2, cyclin B, Cdk2, Chk1, and Chk2. The Poly6207 antibody recognizes phosphorylated human Cdc25A (Ser17) and has been shown to be useful for Western blotting.

Catalogue number:	620702
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	200 microl
Clone:	Poly6207
Gene:	993
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Modified peptide
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A