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Purified anti-FGFR1

Purified anti-FGFR1

Cat no: 616201

Supplier: BioLegend
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FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. This receptor can be upregulated by TGF-beta1 in lung fibroblasts and by platelet derived growth factor-BB in fibroblasts. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM. ThePoly6162 antibody recognizes human FGFR1 (multiple isoforms) and has been shown to be useful for Western blotting.
Catalogue number: 616201
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 50 microl
Clone: Poly6162
Gene: 2260
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: Upon receipt, store frozen at -20 C.
Antigen: Recombinant (partial), N-terminal
Isotype: Rabbit Polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: Fibroblast growth factor receptor 1
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