Purified anti-FLiC (Flagellin)

Cat no: 629701

Supplier: BioLegend

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Description
Additional Information

FliC is a protein expressed in many motile enteric bacteria including Salmonella and Escherichia. The C- and N-terminal regions of the protein among various strains of bacteria are well-conserved. However, there is great variability of length and amino acid sequence in the central region. For example, E. coli flagellin have been reported to vary in size from 36 K to 69 K in MW. The epitope recognized by this FLIC-1 monoclonal antibody is not known. FliC is a subunit protein that polymerizes (in conjunction with other proteins) to form the filaments of bacterial flagella in a precise order. Flagellin is a potent ligand of toll-like receptor 5 (TLR5). By binding to TLR5, flagellin induces activation of NF-kB and triggers the production of cytokines and innate immune responses.

Catalogue number:	629701
Hosts:	Mouse
Applications:	Immunofluorescence, Immunoprecipitation, Western Blot
Size:	25 microg
Clone:	FLIC-1
Gene:	7100
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Flagellin component FliC