Purified anti-Galectin 3

Galectin 3 (also known as galactose-specific lectin 3 and Mac-2 antigen) is a 32 kD member of the galaptin (S-lectin) family, BH-1, that contains carbohydrate recognition domains. This protein forms homo- and hetero-dimers and localizes to the nucleus or cytoplasm depending on proliferation state. Galectin 3 has been shown to modulate allergic reactions and regulate mRNA splicing activity, cell cycle control, and cell adhesion. The expression of galectin 3 can be increased by acetylated LDL, oxidized LDL, and Runx2. Galectin 3 can be modified by phosphorylation and acetylation and has been shown to interact with IgE, galactose, casein kinase I, laminin, mucin, beta-galactoside residues of cell surface, matrix glycoproteins, and some intracellular proteins. The Poly6132 antibody recognizes human and mouse galectin 3 and has been shown to be useful for Western blotting.

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SPECIFICATIONS

Catalog Number

613201

Size

50 microl

Applications

IF, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Clone

Poly6132

Antigen

Recombinant human (partial) , amino acids 151-251.

Gene Id

404021

Isotype

Rabbit polyclonal

Clonality

Polyclonal

Dilutions

Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

-20 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

Upon receipt, store frozen at -20 C.

Alternative Names

Galactose-specific lectin 3, Mac-2 antigen

Regulatory Status

RUO