Purified anti-Gli-1

Cat no: 642402

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

This gene encodes a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined; however, it may play a role in normal development gene transcription. The Gli transcription factors constitute the final effectors of the Hedgehog signalling pathway, which is critical to vertebrate development. Mouse mutation studies indicate possible involvement in human foregut malformation. In addition, both the Ras and Transforming Growth Factor Beta pathways also stimulate and/or induce Gli1 and Gli2 activity independently of Hedgehog ligands.

Catalogue number:	642402
Reactivities:	Human
Hosts:	Rabbit
Applications:	Western Blot
Size:	200 microl
Clone:	Poly6424
Gene:	2735
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Synthetic peptide
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Zinc finger protein GLI1, Glioma-associated oncogene