Purified anti-human C5L2

Cat no: 342402

Supplier: BioLegend

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Description
Additional Information

C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor.

Catalogue number:	342402
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Western Blot
Size:	100 microg
Clone:	1D9-M12
Gene:	27202
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 2.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	GPR77, C5a receptor-like 2, C5a anaphylatoxin chemotactic receptor