Purified anti-human CCRL2

Cat no: 358302

Supplier: BioLegend

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Description
Additional Information

CCRL2 (C-C chemokine receptor-like 2) is a seven transmembrane, G-protein coupled receptor with two isoforms generated from alternative splicing. CCRL2 is expressed by the majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells. In some cell types, its expression is upregulated by inflammatory stimuli. CCRL2 is important for the development of Th2 responses and may act as a decoy receptor capturing and endocyting its ligands CCL5 and CCL19; however, it has been found that CCRL2 captures and retains chemerin/RARRES2 on its cell surface, presenting it to neighboring cells.

Catalogue number:	358302
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	K097F7
Gene:	9034
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Expression vector containing the full sequence of CCRL2
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CCR11, CCR6, CKRX, CRAM, HCR