Purified anti-human CD104

Cat no: 327802

Supplier: BioLegend

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Description
Additional Information

CD104 is a 205 kD type I transmembrane glycoprotein, known as integrin beta4 chain or beta4 integrin, that associates with integrin alpha6 (CD49f) forms alpha6/beta4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.

Catalogue number:	327802
Reactivities:	Human
Hosts:	Mouse
Applications:	ELISA, Flow Cytometry, Immunoprecipitation
Size:	100 microg
Clone:	58XB4
Gene:	3691
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	beta4 integrin, TSP-1180, ,Integrin beta4