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Purified anti-human CD107a (LAMP-1)

Purified anti-human CD107a (LAMP-1)

Cat no: 328601

Supplier: BioLegend
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CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane gly­coprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. It is expressed by activated platelets, acti­vated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. This molecule is located on the luminal side of lysosomes and has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases. Upon activation, CD107a is transferred to the cell membrane surface. It plays a role in cell adhesion and regula­tion of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin.
Catalogue number: 328601
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 25 microg
Clone: H4A3
Gene: 3916
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Human adult adherent peripheral blood cells
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: LAMP1, LGP-120
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