Purified anti-human CD112 (Nectin-2)

Cat no: 337402

Supplier: BioLegend

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Description
Additional Information

CD112, known as poliovirus receptor related 2 protein (PRR2), Nectin-2, or Hve B, is a type I transmembrane glycoprotein, a member of the Ig gene superfamily. It is primarily found on myelomonocytic cells, megakaryocytes, dendritic cells, mast cells, CD34-positive stem cells, endothelial cells, epithelial cells, and neuronal cells. CD112 functions as a receptor for alpha-herpes viruses HSV-1 and pseudorabies virus (PRV). CD112 is an adhesion molecule involved in the formation of cell junction and regulation of NK- and T-cells mediated cytotoxicity through interaction with CD226 (DNAM-1) and other nectin family molecules.

Catalogue number:	337402
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	TX31
Gene:	5819
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Poliovirus Receptor Related 2 Protein (PRR2), Nectin-2, Hve B