Purified anti-human CD131

Cat no: 306102

Supplier: BioLegend

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Description
Additional Information

CD131, also known as the IL-3R common beta subunit (betaC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common beta subunit associates with the specific alpha subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.

Catalogue number:	306102
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunoprecipitation, Western Blot
Size:	100 microg
Clone:	1C1
Gene:	1439
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.5 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Human IL-3R beta chain transfected COS cells
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	IL-3R common beta chain