Purified anti-human CD213a2 (IL13Ralpha2)

Cat no: 354401

Supplier: BioLegend

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Description
Additional Information

CD213a2, also known as IL-13Ralpha2, is a type I transmembrane protein and member of the hematopoietin family. IL13Ra2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Ralpha1/IL-4Ra-mediated IL-13 biological functions. IL13Ralpha2 is expressed by fibroblasts, smooth muscle cells, keratinocytes and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.

Catalogue number:	354401
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	25 microg
Clone:	SHM38
Gene:	3598
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Melanoma cell line A375
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	IL-13RA2, IL-13R, IL13BP, CT19