Purified anti-human CD262 (DR5, TRAIL-R2)

Cat no: 307302

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.

Catalogue number:	307302
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	DJR2-2 (2-6)
Gene:	8795
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 2.0 microg per million cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Extracellular domain of DR5-human IgG1 Fc fusion protein
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	DR5, TRAIL-R2, TRICK2, KILLER, TNFRS10B