Purified anti-human CD300F (IREM-1)

Cat no: 340602

Supplier: BioLegend

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Description
Additional Information

IREM-1 (immune receptor expressed by myeloid cell 1) is a type I single transmembrane protein encoded by human chromosome 17q24.25. A member of the CD300 (CMRF-35) family and the Ig superfamily, IREM-1 is also known as CD300F, or CD300LF (CD300-like member F). CD300F is expressed on monocytes, granulocytes, and myeloid leukemia cell lines. The cytoplasmic domain of IREM-1 contains an ITIM and associates with the P85alpha subunit of PI3K (phosphoinositide 3-kinase). IREM-1 also functions as an inhibitory receptor.

Catalogue number:	340602
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunoprecipitation
Size:	100 microg
Clone:	UP-D2
Gene:	146722
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CD300LF, IREM-1, IgSF13