Purified anti-human CD307e (FcRL5)

Cat no: 340302

Supplier: BioLegend

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Description
Additional Information

FcRL5, also known as CD307e, CD307, IRTA2, FcRH5 and BXMAS1, is a 106kD type I transmembrane glycoprotein composed of 6-8 extracellular Ig like C2 domains and 2 cytoplasmic ITIM motifs. The FcRL5 gene is located on chromosome 1q21 and is normally expressed by tonsillar plasma cells and germinal center B cells. It has been suggested that FcRL5 contributes to B cell maturation and B cell receptor modulation. The identification of FcRL5 on a number of transformed cell types including hairy cell leukemia, mantle cell lymphoma, chronic lymphocytic lymphoma and Burkitt’s lymphoma has prompted interest in it as a potential biomarker or target for immunotherapy. FcRL5 binds all aggregated IgG isotypes.

Catalogue number:	340302
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunoprecipitation
Size:	100 microg
Clone:	509f6
Gene:	83416
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.125 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	P815 cells transfected with FcRL5
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	CD307, IRTA2, FcRH5, IFGP5, BXMAS1