Purified anti-human CD328 (Siglec-7)

Cat no: 347702

Supplier: BioLegend

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Description
Additional Information

Siglec-7 is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs), also known as p75/AIRM1. It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with alpha2,8 disialyl and alpha2,6 sialyl residues.

Catalogue number:	347702
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunoprecipitation
Size:	100 microg
Clone:	S7.7
Gene:	27036
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Siglec-7 3T3 transfected cells
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	QA79 membrane protein, Adhesion inhibitory receptor molecule 1, p75/AIRM1, D-siglec