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Purified anti-human CD349 (Frizzled-9)

Purified anti-human CD349 (Frizzled-9)

Cat no: 326701

Supplier: BioLegend
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CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/beta-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 isan important factor fornervous system development and is critical for hippocampal development.
Catalogue number: 326701
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 microg
Clone: W3C4E11
Gene: 8322
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?2.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: WERI-RB-1 retinoblastoma cells
Isotype: Mouse IgM, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Frizzled-9 receptor, Frizzled-9, Fz9, FZD9, FzE6, hFz9
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