Purified anti-human IL-1 RA

Cat no: 509901

Supplier: BioLegend

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Description
Additional Information

Interleukin-1 receptor antagonist (IL-1RA) is composed of three isoforms, one secreted (sIL-1Ralpha/IL-1Ralpha1), two intracellular (IL-1Ralpha2/IL-1Ralpha3) and produced by monocytes, tissue macrophages, Langerhans cells, dendritic cells, T and B cells, natural killer (NK) cells, large granular lymphocytes (LGL), vascular endothelium, smooth muscle, fibroblasts, thymic epithelia, astrocytes, microglia, glioma cells, keratinocytes, and chondrocytes. It is upregulated by IL-1beta, IL-4, IL-6 and downregulated by glucocorticoids. The JK1RA-1 antibody reacts with human interleukin-1 receptor antagonist (IL-1RA).

Catalogue number:	509901
Reactivities:	Human
Hosts:	Mouse
Size:	50 microg
Clone:	JK1RA-1
Gene:	3557
Dilutions:	Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 4-6 microg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Recombinant human IL-1 receptor antagonist
Isotype:	Mouse IgG1
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Interleukin-1 receptor antagonist, IRAP, ILS, MG50, IL-1RN, IL-1 inhibitor, IL-1 inhibitory activity