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Purified anti-human/mouse CD266 (Fn14, TWEAK Receptor)
BioLegend

Supplier:

BioLegend

Cat no: 314102

Purified anti-human/mouse CD266 (Fn14, TWEAK Receptor)

CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia.

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SPECIFICATIONS

Catalog Number

314102

Size

100 microg

Applications

FC, IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse

Clone

ITEM-4

Antigen

Human Fn14 transfected P815

Gene Id

27279,51330

Isotype

Mouse IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

Fn14, TWEAK Receptor, TNFRSF12a

Regulatory Status

RUO

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

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