Purified anti-Human Podoplanin

Cat no: 337001

Supplier: BioLegend

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Description
Additional Information

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, or Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution including many mesothelial cells, epithelial cells, follicular dendritic cells and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC-2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

Catalogue number:	337001
Reactivities:	Human
Hosts:	Rat
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	25 microg
Clone:	NC-08
Gene:	10630
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at 1.0 microg per 106 cells in 100 microl volume or 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Rat IgG2a, lambda
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	T1a, gp38, stromal cell marker