Purified anti-human RANTES

Cat no: 510201

Supplier: BioLegend

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Description
Additional Information

RANTES is a 7.8 kD member of the CC family of chemokines, also known as CCL5, which is expressed in T cells and monocytes/macrophages. RANTES is strongly chemotactic for monocytes/macrophages, memory T cells, eosinophils, and induces histamine release from basophils. In solution, RANTES can form high molecular weight aggregates that exhibit dissimilar biological activities to the dimeric form. Aggregates cause T cell and neutrophil activation while promoting HIV infection, whereas, the dimeric form exhibits RANTES-induced chemotaxis and inhibits HIV infection. Interestingly, as T cells become activated RANTES secretion appears to decrease.

Catalogue number:	510201
Reactivities:	Human
Hosts:	Mouse
Size:	50 microg
Clone:	BL-5030
Gene:	6352
Dilutions:	Each lot of this protein is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 0.5-2 microg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Recombinant human RANTES
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Normal T cell Expressed and Secreted (RANTES), sisdelta, CCL5