Purified anti-human TCR Valpha24-Jalpha18 (iNKT cell)

Cat no: 342902

Supplier: BioLegend

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Description
Additional Information

Encoded by the TCR Valpha24-Jalpha18 germline configuration, Valpha24-JalphaQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Valpha24-JalphaQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.

Catalogue number:	342902
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 microg
Clone:	6B11
Gene:	28659
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	TCR Valpha24-Jalpha18, TCR Valpha24-JalphaQ, invariant NKT cell, iNKT