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Purified anti-human Tim-4

Purified anti-human Tim-4

Cat no: 354001

Supplier: BioLegend
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The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th-1 and Th-2) cell-mediated immunity. Tim-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of Tim-1. This binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and is connected to TIM-1-triggered Th2 responsiveness.
Catalogue number: 354001
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 microg
Clone: 9F4
Gene: 91937
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Human TIM-4- IgV Fc, fusion protein
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: SMUCKLER (Spleen, mucin-containg, knock-out of lymphotoxin (LT)), TIMD4, T-cell immunoglobulin and mucin domain containing 4
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