Purified anti-IDO2

Cat no: 654401

Supplier: BioLegend

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Description
Additional Information

Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1/IDO, and may play a role in T and B cell immunity. IDO2 is not as widely expressed as IDO, but like its relative, it is also expressed in antigen-presenting dendritic cells where tryptophan catabolism drives immune tolerance. Like IDO, IDO2 catabolizes tryptophan, triggers phosphorylation of the translation initiation factor eIF2alpha, and mobilizes translation of LIP, an inhibitory isoform of the immune regulatory transcription factor NF-IL6 (nuclear factor for interleukin-6).

Catalogue number:	654401
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Western Blot
Size:	125 microl
Clone:	Poly26544
Gene:	169355, 209176
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, use 20microl - 25 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Antigen:	Complete protein containing a mixture of human and mouse IDO2 H6-tagged protein.
Isotype:	Rabbit Polyclonal IgG
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Indoleamine 2,3-dioxygenase 2, INDOL1, Indoleamine 2,3-dioxygenase-like protein 1