Home  >  Products  >  Purified anti-Lyn
Purified anti-Lyn

Purified anti-Lyn

Cat no: 628102

Supplier: BioLegend
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Lyn is a tyrosine protein kinase and a member of the src subfamily. Two isoforms of Lyn have been reported: Lyn A, 53 kD and Lyn B, 56 kD. Lyn is predominantly expressed in macrophages, B cells, and platelets. Lyn exhibits both stimulatory activity (mast cells) and inhibitory activity (B cells), and has been shown to increase p53 levels and inhibit nuclear export. Recent reports have suggested that Lyn may participate in the induction of apoptosis by genotoxic agents. Lyn has been shown to be activated in late G1 by stem cell factor and is increased in myeloid leukemias. Lyn interacts with the high affinity IgE receptor, actin cytoskeleton, gamma-tubulin, and p53. The LYN-01 monoclonal antibody recognizes the human, mouse, and rat Lyn and has been shown to be useful for Western blotting, immunoprecipitation, and immunocytochemistry.
Catalogue number: 628102
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Size: 100 microg
Clone: LYN-01
Gene: 4067
Dilutions: Each lot of this antibody has been quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 microg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Partial recombinant Lyn (aa 8-238) expressed in bacteria
Isotype: Mouse IGg1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Tyrosine protein kinase Lyn
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave