Home  >  Products  >  Purified anti-MAPKAP1
Purified anti-MAPKAP1

Purified anti-MAPKAP1

Cat no: 648802

Supplier: BioLegend
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
SIN1 encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Recent studies have shown that it is identical to MIP1 for MEKK2 interacting protein 1. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Within mTORC2, MAPKAP1 is required for complex formation and mTORC2 kinase activity. MAPKAP1 inhibits MAP3K2 by preventing its dimerization and autophosphorylation. It inhibits HRAS and KRAS signaling and enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.
Catalogue number: 648802
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100 microl
Clone: Poly6488
Gene: 79109
Dilutions: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.8-1.5 microg antibody per ml dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Antigen: Recombinant protein
Isotype: Rabbit Polyclonal
Clonality: Polyclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: -20 C
Alternative names: Mitogen-activated protein kinase associated protein 1, Target of rapamycin complex 2 subunit MAPKAP1, SAPK-interacting protein 1, Sin1, MIP1
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave