Purified anti-Mcl-1

Cat no: 613601

Supplier: BioLegend

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Description
Additional Information

Mcl-1 (myeloid cell leukemia-1) is a 37 kD Bcl-2 related protein found in mitochondrial and non-mitochondrial membranes that dimerizes with Bax. Mcl-1 has been shown to act as a survival factor for hematopoietic cells and contribute to the STAT-dependent protection of neutrophils against apoptosis. Mcl-1 is increased by PMA, GM-CSF, M-CSF, IL-1beta, IL-3, and IL-6 in hematopoietic cells. This protein is decreased following growth factor withdrawal. Mcl-1 is modified by JNK phosphorylation. The Poly6136 antibody has been shown to recognize mouse Mcl-1 and has been shown to be useful for Western blotting.

Catalogue number:	613601
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Western Blot
Size:	50 microl
Clone:	Poly6136
Gene:	4170
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Recombinant (partial)
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Myeloid cell leukemia-1