Purified anti-MCM2

Cat no: 602201

Supplier: BioLegend

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Description
Additional Information

The MCM2 protein (minichromosome maintenance protein 2) is a 120 kD member of the MCM family that forms a heterotetramer with other family members. This nuclear protein functions in eukaryotic genome replication. MCM2 forms a complex with MCM4, MCM6, and MCM7. MCM2 regulates the helicase activity of the pre-replication complex and is involved in the formation of replication forks. MCM2 is regulated by protein kinases Cdc2 and Cdc7 and can be modified by phosphorylation. The Poly6022 antibody recognizes the C-terminal region of both human and mouse MCM2 and has been shown to be useful for Western blotting.

Catalogue number:	602201
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	50 microl
Clone:	Poly6022
Gene:	4171
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1:100~1:400. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Recombinant (partial), C-terminal
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Minichromosome maintenance protein 2, Cdc19