Purified anti-MCM4

Cat no: 602402

Supplier: BioLegend

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Description
Additional Information

The MCM4 protein (minichromosome maintenance protein 4) is a nuclear 100 kD DNA-dependent ATPase. The MCM4 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM4 together with MCM6 and MCM7 have DNA helicase activity. MCM4 can be modified by phosphorylation by CDK2. Phosphorylation of MCM4 inhibits DNA replication. MCM4 has been reported to interact with the MCM6 and MCM7 (to form a 600 kD complex with helicase activity) and CDK2. The Poly6024 antibody recognizes human MCM4 and has been shown to be useful for Western blotting.

Catalogue number:	602402
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunoprecipitation, Western Blot
Size:	200 microl
Clone:	Poly6024
Gene:	4173
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Peptide
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Minichromosome maintenance protein 4