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Purified anti-mouse CD119 (IFN-gamma R alpha chain)

Purified anti-mouse CD119 (IFN-gamma R alpha chain)

Cat no: 112802


Supplier: BioLegend
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CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-gammaRalpha chain. It is a class II cytokine receptor family member that serves as a IFN-gamma-binding chain associated with the IFN-gamma beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-gamma initiates and regulates a variety of immune responses.
Catalogue number: 112802
Reactivities: Mouse
Hosts: Hamster
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 500 microg
Clone: 2E2
Gene: 15979
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Soluble recombinant mouse IFN-gammaR alpha chain protein
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IFN-gammaRalpha , IFN-gamma Receptor alpha chain, CDw119
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