Purified anti-mouse CD120a (TNF R Type I/p55)

Cat no: 113001

Supplier: BioLegend

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Description
Additional Information

CD120a is a 55 kD Type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type I (TNFRI) or p55. It is expressed on a variety of cells at low levels. Resting T cells and erythrocytes express very little to no CD120a. This receptor binds both TNF-alpha and LT-alpha (also known as TNF-beta). In association with TRADD and RIP, the receptor crosslinking induced by TNF-alpha or LT-alpha trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Catalogue number:	113001
Reactivities:	Mouse
Hosts:	Hamster
Applications:	Flow Cytometry, Immunoprecipitation, Western Blot
Size:	50 microg
Clone:	55R-286
Gene:	21937
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	E. coli-expressed extracellular domain of the mouse TNFRI protein
Isotype:	Armenian Hamster IgG
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	TNFR type I, TNFRI, TNFR60, p55, TNFRSF1A