Purified anti-mouse CD179a (VpreB)

Cat no: 143601

Supplier: BioLegend

0 reviews | Write a Review Pencil

Description
Additional Information

CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the beta strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.

Catalogue number:	143601
Reactivities:	Mouse
Hosts:	Rat
Applications:	ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
Size:	25 microg
Clone:	R3
Gene:	22362
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?1.0 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Soluble mouse VpreB protein
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	VpreB1, pre-B lymphocyte 1