Purified anti-mouse CD256 (APRIL)

Cat no: 136702

Supplier: BioLegend

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Description
Additional Information

CD256 (APRIL, TNFSF13, TALL2, TRDL1) a transmembranal protein of 26 kD, forms a homotrimeric molecule that is cleaved from the cell surface resulting in the soluble form of APRIL; it also forms heterotrimers with BLyS. Its receptor are TNFRSF13b/TACI and TNFRSF17/BCMA. Expressed by T cells, B cells, dendritic cells, monocytes, and macrophages, APRIL induces proliferation of T and B cells, promotes IgA class switching, downregulates T-cell dependent antibody responses, and regulates the growth of a variety of tumor cells.

Catalogue number:	136702
Reactivities:	Mouse
Applications:	ELISA, Flow Cytometry, Immunocytochemistry
Size:	500 microg
Clone:	A3D8
Gene:	69583
Dilutions:	Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Fusion protein of murine Maltose binding protein (MBP) and soluble April
Isotype:	Armenian Hamster IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	TNFSF13, TALL2, TRDL1