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Purified anti-mouse CD268 (BAFF-R)

Purified anti-mouse CD268 (BAFF-R)

Cat no: 134102

Supplier: BioLegend
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BAFF (B cell-activating factor belonging to the TNF family) receptor (BAFF-R) is one of the three receptors that bind to BAFF. It is a type III transmembrane TNF receptor family member. BAFF-R is expressed at high levels in resting B cells and at lower levels in activated B cells, a small subset of activated/memory CD4+ T cells. It is a major mediator of BAFF dependent co-stimulatory response in peripheral B and T cells. It was reported that the mice expressing defective BAFF-R have disrupted B cell maturation. BAFF receptor appears to be particularly important for the regulation of normal B cell survival and maturation, as well as in the pathophysiology of aggressive B-cell malignancies and autoimmune diseases.
Catalogue number: 134102
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 500 microg
Clone: 7H22-E16
Gene: 72049
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Mouse BAFF receptor transfected rat RBL cells
Isotype: Rat IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: BR3, BAFFR, TNFRSF13C, B cell-activating factor receptor, BLys receptor 3
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