Purified anti-mouse CD49e

Cat no: 103801

Supplier: BioLegend

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Description
Additional Information

CD49e is a 135 kD protein, also known as alpha5 integrin or VLA-5 alpha chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin beta1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells.

Catalogue number:	103801
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunohistochemistry
Size:	50 microg
Clone:	5H10-27(MFR5)
Gene:	16402
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	(C57BL/6 x A/J)F1 mouse mast cell line
Isotype:	Rat IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	alpha5 integrin, VLA-5 alpha chain, Integrin alpha5