Purified anti-mouse CD79b (Igbeta)

Cat no: 132802

Supplier: BioLegend

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Description
Additional Information

Mouse CD79b (Igbeta chain) is a 35-40kD transmembrane protein that forms a heterodimer with CD79a (30-35 kD, Ig alpha chain).The CD79b and CD79a hererodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells.CD79b participates signal transduction involved in the development of B cells as well. It was reported that association between CD79b/CD79a with IgM is essential in inducing both the transition from progenitor to precursor B cells and subsequent allelic exclusion.Igbeta knockout mice had a complete block in B cell development at the immature CD43+B220+ stage. The HM79b-12 react with an extracellular epitope of CD79b or Ig beta.

Catalogue number:	132802
Reactivities:	Mouse
Applications:	Flow Cytometry
Size:	500 microg
Clone:	HM79-12
Gene:	15985
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Isotype:	Armenian Hamster IgG
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Ig beta chain