Purified anti-mouse H-2Ld/H-2Db

Cat no: 114502

Supplier: BioLegend

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Description
Additional Information

The 28-14-8 antibody reacts with the H-2Db MHC class I alloantigen expressed on nucleated cells from mice of the H-2Db haplotype. H-2Db is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. The 28-14-8 antibody has been reported to block antigen-specific lysis of target cells by cytotoxic T lymphocytes. The 28-14-8 antibody cross-reacts with the H-2Ld haplotype. Clone 28-14-8 recognizes the alpha3 domain of H-2Db.

Catalogue number:	114502
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	500 microg
Clone:	28-14-8
Gene:	14964,14972
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	C3H.SW mouse splenocytes
Isotype:	Mouse(C3H/HeJ) IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	MHC Class I