Purified anti-mouse/human Bcl-6

Cat no: 648301

Supplier: BioLegend

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Description
Additional Information

B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells.

Catalogue number:	648301
Reactivities:	Human, Mouse
Hosts:	Mouse
Applications:	Immunohistochemistry, Western Blot
Size:	25 microg
Clone:	IG191E/A8
Gene:	604
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 microg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	Plasmid vector containing cDNA of the Bcl-6 gene
Isotype:	Mouse IgG1
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	BCL6