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Purified anti-mouse/human CD258 (LIGHT)
BioLegend

Supplier:

BioLegend

Cat no: 137102

Purified anti-mouse/human CD258 (LIGHT)

CD258, also known as LIGHT, belongs to the tumor necrosis factor (TNF) superfamily. CD258 is a homotrimer composed of type II single-pass chains. The cleavage of this molecule from the cell surface results in a soluble form of LIGHT. CD258 stimulates T cell proliferation, CTL activity, Th1 cytokine production and induces apoptosis in some tumor lines. CD258 is expressed by T cells, NK cells, macrophages and platelets. The receptors of LIGHT are HVEM, LTbetaR and DCR3. CD258 has an important role in the cell-mediated immune response and in graft versus host disease.

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SPECIFICATIONS

Catalog Number

137102

Size

500 microg

Applications

ELISA, IP

Hosts

Mouse

Reactivities

Hum, Mouse

Clone

15B2

Antigen

Recombinant extracellular domain of murine LIGHT

Gene Id

50930, 8740

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by ELISA. For ELISA, the suggested use of this reagent is 10 microg/ml. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C.

Alternative Names

LIGHT, TNFSF14, LTgamma, HVEM-L, Ly113, TR2

Regulatory Status

RUO

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

More info

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