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Purified anti-mouse/human Mac-2 (Galectin-3)

Purified anti-mouse/human Mac-2 (Galectin-3)

Cat no: 126701


Supplier: BioLegend
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Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and epsilonBP. It is a member of animal beta-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to beta-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.
Catalogue number: 126701
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Size: 50 microg
Clone: Gal397
Gene: 16854,3958
Dilutions: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested working dilution is 0.5-1.0 microg/ml antibody dilution buffer for each mini-gel. For immunofluorescent staining, the suggested use of this reagent is ?0.5 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C.
Concentration: 0.5 mg/ml
Antigen: Recombinant (partial), amino acids 151-251
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: Galectin-3, Mac-2
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